
Mesalazine / 5-Aminosalicylic acid
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Description
Water soluble
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Mesalazine, also called 5-Aminosalicylic Acid or 5-ASA, is a trusted anti-inflammatory compound widely used in treating gastrointestinal conditions, especially inflammatory bowel disease (IBD). Moreover, its alternative names, including 2-Hydroxy-5-aminobenzoic acid, reflect its versatility. With the molecular formula C7H7NO3 and a molecular weight of 153.14 g/mol, Mesalazine ensures precision in addressing inflammation.
Additionally, Mesalazine works as an IKK inhibitor, which enhances its effectiveness in reducing inflammation. Appearing as a white to off-white powder, it highlights high purity standards for pharmaceutical applications. Furthermore, its boiling point of 276°C and density of 1.3585 indicate excellent stability across various conditions. Because of its robust chemical structure, it is dependable for many medical uses.
Although its water solubility is limited (less than 0.1 g/100 ml at 21°C), Mesalazine remains essential in oral and topical formulations. This makes it highly effective for localized and targeted inflammation treatment. Additionally, it is securely packaged in 25 kg drums, ensuring safe handling and efficient storage. Its decomposition point of 279-281°C further confirms its structural reliability under controlled environments.
Thanks to these properties, Mesalazine is ideal for managing inflammation in chronic conditions like ulcerative colitis and Crohn’s disease. Besides its anti-inflammatory properties, its physical and chemical stability adds to its dependability. By combining targeted effects with pharmaceutical-grade quality, Mesalazine continues to be vital in medical and research advancements.